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Dharma Lapiss HEMA Dentin Desensitizer Solution · 10 mL
SKU 076-1075MFR# 20-00041
Pack
10 mL
10 mL$21.99
No description available yet.
Product
- Manufacturer
- Dharma
- Manufacturer #
- 20-00041
- Item code
- 076-1075
Catalog path
- Marketplace
- Clinical
- Category
- Preventive
- Subcategory
- Desensitizers
Ordering
- Status
- Ships in 3 business days
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About desensitizers
Dentin hypersensitivity is a short, sharp pain from exposed dentin in response to stimuli that are normally harmless: gentle touch, mild cold or heat, sweet or acid food and drink, and a blast of air. It is generally regarded as needing exposed dentin, especially open dentinal tubules, and a pulp nerve that responds to the outside environment. The most widely accepted explanation is the hydrodynamic theory: mechanical, thermal and chemical changes move fluid inside the tubules, which stimulates nerve terminals at the tubule walls and causes a brief acute pain. A review cited by the ADA puts dentin hypersensitivity at about 11.5 percent of patients.
Desensitizing agents work in one of two ways: they block the openings of the dentinal tubules, or they act on the pulp nerves directly. In-office products come as gels, solutions, varnishes, resin sealers, glass ionomers and dentin adhesives; at-home products are toothpastes, mouthwashes and chewing gums. The FDA has cleared fluoride varnish as a device for use as a cavity liner and a root desensitizer, to reduce sensitivity to temperature and touch on root surfaces exposed by receding gingiva. Silver diamine fluoride is classified by the FDA as a Class II device cleared for the treatment of tooth sensitivity, the same type of clearance fluoride varnish has, and must be professionally applied. Cavity varnish, a compound that coats a prepared cavity before the restorative material goes in, is a Class II device with special controls (21 CFR 872.3260).
How desensitizing agents differ
Potassium salts were thought to decrease the excitability of the pulp nerves, but a review reports that soundly designed trials have not shown potassium to be effective at desensitizing teeth.
Glutaraldehyde is thought to react with serum albumin in the tubule fluid, forming a precipitate that narrows or blocks the tubules.
Oxalate and arginine-calcium products have been shown to precipitate and occlude the tubules and form a protective layer at the dentin surface.
Dental adhesives and resin sealants seal the tubules by forming a physical barrier that blocks the dentinal fluid flow. Glass ionomers can occlude open tubules by precipitating a hydroxycarbonate apatite layer over the openings.
What to look at when choosing a desensitizer
How long it lasts: a review notes that keeping an occluding agent inside the tubules is a challenge in the mouth, and that the long-term effect of these agents remains unclear.
Evidence: recent systematic reviews found that most agents that occlude the dentin tubules chemically or physically differed significantly from placebo in reducing the symptom.
Active ingredient in a paste: a 2023 systematic review and network meta-analysis concluded that twice-daily self-applied stannous, potassium with or without stannous, or arginine can be recommended for reducing dentine hypersensitivity pain.
Sources: Liu et al. 2020, Pathogenesis, diagnosis and management of dentin hypersensitivity: an evidence-based overview (BMC Oral Health) · CDC: Recommendations for Using Fluoride to Prevent and Control Dental Caries in the United States (MMWR 2001;50(RR-14)) · ADA Oral Health Topics: Fluoride — Topical and Systemic Supplements · FDA 21 CFR 872.3260, Cavity varnish · ADA Oral Health Topics: Toothpastes
