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Zest MicroPrime G Desensitizer

Zest MicroPrime G Desensitizer · 10 mL Bottle

SKU 111-0090MFR# 90814-M
Size 10 mL Bottle
MicroPrime G - Desensitizing Agent, 10 mL Bottle. Glutaraldehyde desensitizer eliminates post-op sensitivity. Can be used alone on cervical erosions and as an addition to bonding procedures. Compatible with total-etch and self-etch bonding systems as well as cements and amalgam.

Product

Manufacturer
Zest Dental Solutions
Manufacturer #
90814-M
Item code
111-0090

Catalog path

Marketplace
Clinical
Category
Preventive
Subcategory
Desensitizers

Ordering

Status
In stock

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Questions

What is Zest MicroPrime G Desensitizer used for?

MicroPrime G - Desensitizing Agent, 10 mL Bottle.

Which size options are on this page?

This page carries 3 size options: 10 mL Bottle, Unit Dose, 50 × 0.2 mL, 5 mL Bottle. Pick one to see its price, part number and stock.

When does it ship?

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About desensitizers

Dentin hypersensitivity is a short, sharp pain from exposed dentin in response to stimuli that are normally harmless: gentle touch, mild cold or heat, sweet or acid food and drink, and a blast of air. It is generally regarded as needing exposed dentin, especially open dentinal tubules, and a pulp nerve that responds to the outside environment. The most widely accepted explanation is the hydrodynamic theory: mechanical, thermal and chemical changes move fluid inside the tubules, which stimulates nerve terminals at the tubule walls and causes a brief acute pain. A review cited by the ADA puts dentin hypersensitivity at about 11.5 percent of patients.

Desensitizing agents work in one of two ways: they block the openings of the dentinal tubules, or they act on the pulp nerves directly. In-office products come as gels, solutions, varnishes, resin sealers, glass ionomers and dentin adhesives; at-home products are toothpastes, mouthwashes and chewing gums. The FDA has cleared fluoride varnish as a device for use as a cavity liner and a root desensitizer, to reduce sensitivity to temperature and touch on root surfaces exposed by receding gingiva. Silver diamine fluoride is classified by the FDA as a Class II device cleared for the treatment of tooth sensitivity, the same type of clearance fluoride varnish has, and must be professionally applied. Cavity varnish, a compound that coats a prepared cavity before the restorative material goes in, is a Class II device with special controls (21 CFR 872.3260).

How desensitizing agents differ

Potassium salts were thought to decrease the excitability of the pulp nerves, but a review reports that soundly designed trials have not shown potassium to be effective at desensitizing teeth.

Glutaraldehyde is thought to react with serum albumin in the tubule fluid, forming a precipitate that narrows or blocks the tubules.

Oxalate and arginine-calcium products have been shown to precipitate and occlude the tubules and form a protective layer at the dentin surface.

Dental adhesives and resin sealants seal the tubules by forming a physical barrier that blocks the dentinal fluid flow. Glass ionomers can occlude open tubules by precipitating a hydroxycarbonate apatite layer over the openings.

What to look at when choosing a desensitizer

How long it lasts: a review notes that keeping an occluding agent inside the tubules is a challenge in the mouth, and that the long-term effect of these agents remains unclear.

Evidence: recent systematic reviews found that most agents that occlude the dentin tubules chemically or physically differed significantly from placebo in reducing the symptom.

Active ingredient in a paste: a 2023 systematic review and network meta-analysis concluded that twice-daily self-applied stannous, potassium with or without stannous, or arginine can be recommended for reducing dentine hypersensitivity pain.

Sources: Liu et al. 2020, Pathogenesis, diagnosis and management of dentin hypersensitivity: an evidence-based overview (BMC Oral Health) · CDC: Recommendations for Using Fluoride to Prevent and Control Dental Caries in the United States (MMWR 2001;50(RR-14)) · ADA Oral Health Topics: Fluoride — Topical and Systemic Supplements · FDA 21 CFR 872.3260, Cavity varnish · ADA Oral Health Topics: Toothpastes