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Dharma Calix-E 17% EDTA Solution with Surface Modifiers
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Dharma Calix-E 17% EDTA Solution with Surface Modifiers · 500 mL

SKU 076-1091MFR# 28-00021
Size 500 mL
120 mL$8.59 500 mL$16.59

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Product

Manufacturer
Dharma
Manufacturer #
28-00021
Item code
076-1091

Catalog path

Marketplace
Clinical
Category
Endodontics

Ordering

Status
Ships in 3 business days

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About EDTA and chelating agents

EDTA has been the most widely advocated chelating agent for dissolving the smear layer since it was introduced to endodontics in 1957. The most extensively studied and internationally accepted concentration is 17 percent. How well it works depends on concentration, pH, contact time and whether it is a solution or a gel.

An intracanal medicament is placed in the canal to act on what is left in it; disinfection combines mechanical debridement with these medicaments. The canal preparation materials beside them are the gels and solutions used while the canal is being shaped.

During instrumentation a smear layer forms on the canal walls, which may get in the way of disinfection. EDTA removes it by chelating the calcium in the inorganic part of dentine, and is used as a final rinse together with sodium hypochlorite, which deals with the organic part.

How medicaments, chelating agents and canal prep gels differ
  • Medicaments — Left in the canal between visits, rather than rinsed through it. A paste is placed with a syringe, a rotary spiral or a purpose-made carrier.
  • EDTA & Chelating Agents — Works on the inorganic part of the smear layer, where hypochlorite works on the organic part.
  • Canal Prep Gels & Lubricants — Thick enough to stay where it is put, rather than running through the canal. One study reported the solution forms diffusing better than the viscous gels.
  • Pulp Vitality Testers — Cold sprays in a can, filed for pulp vitality testing.
What to look at when choosing a medicament or canal prep material

Placement: one study found a purpose-made paste carrier left a denser fill of calcium hydroxide than a syringe with a finger spreader or a syringe with a rotary spiral.

Getting it out again: the difficulty of removing a medicament from the canal before filling has been reported to work against the result of treatment.

Form: the same active material can come as a paste in a syringe, a powder to mix, a solution or a gel.

Sources: Effectiveness of calcium hydroxide as an intracanal medicament in endodontic retreatment, 2025 (J Conserv Dent Endod) · Comparative Evaluation of Smear Layer Removal Efficacy of EDTA Gel Versus Solution With Sonic Activation, 2026 (Cureus) · Intracanal placement of calcium hydroxide: a comparison of a specially designed paste carrier technique with other techniques, 2013 (BMC Oral Health) · Comparative evaluation of irrigant activation devices for removal of calcium hydroxide, 2026 (BMC Oral Health)